Table 2.
Anti-inflammatory effects of CB2 activation in animal models
| Animal model for disease | Reference |
|---|---|
| Inflammatory pain and ischemic stroke | (Yu et al., 2010; Pini et al., 2012) |
| Alzheimer’s disease (AD) | (Martin-Moreno et al., 2012) |
| Colitis | (Storr et al., 2009) |
| Acute hind paw inflammation | (Berdyshev et al., 1998) |
| Acute lung injury | (Conti et al., 2002) |
| Sepsis | (Tschop et al., 2009) |
| Ischemic injury | (Fernandez-Lopez et al., 2006) |
| ALS | (Kim et al., 2006) |
| Viral MS model | (Mestre et al., 2009) |
| Stroke (ischemia and reperfusion) | (Zhang et al., 2007; Zhang et al., 2009; Murikinati et al., 2010; Tuma and Steffens, 2012) |
| EAE | (Docagne et al., 2007) |
| Alcoholic liver disease | (Louvet et al., 2011) |