Table 1.

Suzuki-Miyaura Cross-Coupling of Various Aryl Halides with Dioxolanylethyltrifluoroborate 1 ^a

entry	electrophile	product	isolated yield (%)
1			89 (Br) 82b (Br) 74 (Cl)
2			56
3			83
4			48 (Br) 0c (Cl)
5			70
6			62
7			90
8			38 (Br) 82 (Cl)
9			59
10			71 (Br) 55 (Cl)
11			50d
12			68d
13			69
14			38e

^aReaction conditions: Aryl halide (1.0 equiv), organotrifluoroborate (1.1 equiv), PdCl₂A^taPhos₂ (5 mol %), Cs₂CO₃ (3.0 equiv), toluene/H₂O (4:1, [ ] = 0.25 M), 100 °C, 14 h.

^bUsing 2.5 mol % catalyst.

^cA mixture of aryl chloride and boronic acid was recovered.

^dProduct contains up to 8 % impurity.

^eReaction performed on a 3 mmol scale using a 1 : 1 trifluoroborate/electrophile ratio and only 1 mol % Pd.