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Representative ATDs of z/n = +2/1 of R2/wt (a,b) and z/n = +3/2 of R2/ΔK280 (c,d) before and after the addition of heparin. For the samples containing heparin, the ATDs are collected after 24-hour incubation. Features associated to monomers and dimers are labeled with M and D respectively.