Table 1.
Allele and genotype frequencies of the FSHR genetic variants in women with PCOS (n = 384) and healthy controls (n = 768). H-W test = Hardy-Weinberg equilibrium test
| ALLELE | P | OR (95 % CI) | GENOTYPE | P | H-W test | ||||
|---|---|---|---|---|---|---|---|---|---|
| 307 | Thr | Ala | Thr/Thr | Thr/Ala | Ala/Ala | ||||
| case | 540(0.703) | 228(0.297) | 0.39 | 1.09 (0.90 ~ 1.31) | 192(0.500) | 156(0.406) | 36(0.094) | 0.66 | 0.60 |
| control | 1053(0.686) | 483(0.314) | 362(0.471) | 329(0.428) | 77(0.100) | 0.86 | |||
| 680 | Asn | Ser | Asn/Asn | Asn/Ser | Ser/Ser | ||||
| case | 536(0.698) | 232(0.302) | 0.45 | 1.08 (0.89 ~ 1.30) | 187(0.487) | 162(0.422) | 35(0.091) | 0.75 | 0.99 |
| control | 1048(0.682) | 488(0.318) | 357(0.465) | 334(0.435) | 77(0.100) | 0.93 | |||