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Serial sections of colonic biopsy samples for in situ hybridisation (ISH) of REGs (a–e) with corresponding immunohistochemistry (IHC) for cell-type markers DEFA6 (e–g) and serotonin (h). Metaplastic Paneth cell (arrows in a-c, e-g). Enteroendocrine cell (arrows in d, h) Bar 30 μm. Sections a-c and e-g from un-inflamed ulcerative colitis. Sections d and h from pseudomembraneous colitis
