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Serial sections of a sample of un-inflamed mucosa from the hepatic flexure of a patient with Crohn’s disease. IHC for serotonin (a) and ISH for REG4 (b) and CgA (c) expression (CGA chromogranin A). A clear overlap of expression can be seen for all three markers, with the number of positive cells being highest for CgA and the lowest for REG4
