Fig. 6.

The effects of verapamil, AEO solution, and cyclosporin A on recombinant human Pgp membrane. Description of data: Standardization of the assay, confirming that verapamil stimulates, cyclosporin A inhibits, and the AEO solution has no effect on Pgp ATPase activity. The effect of these agents on ATP consumption was compared with basal ATP consumption (which was measured based on the difference between ATP consumption in the presence and absence of sodium orthovanadate, a Pgp ATPase activity inhibitor)