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(A-C) Schemas of all three trials. Black arrows indicate timing of LVEF (left ventricular ejection fraction) measurement reported in this analysis. q2w, every 2 weeks; qw, weekly; q3w, every 3 weeks; MUGA, multigated radionuclide angiography. (*) Pegfilgrastim was given subcutaneously on day 2 after chemotherapy.
