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. Author manuscript; available in PMC: 2014 Feb 15.
Published in final edited form as: Eur J Pharmacol. 2012 Dec 28;701(0):176–180. doi: 10.1016/j.ejphar.2012.12.024

Fig. 2.

Fig. 2

Percentage change in monoamine and respective metabolite levels in the striatum (A) or frontal cortex (B) of rats that received saline (open bars) or MDMA (10mg/kg × 4, filled bars). For the saline group, mean (± S.E.M.) quantities (ng/100 mg tissue) of 5-HT, 5-HIAA, dopamine, DOPAC, and HVA were 22.0 (±1.7), 14.0 (±1.0), 504.9 (±4.0), 82.4 (±6.1), and 53.8 (±3.3) in the striatum, and 18.7 (±2.2), 9.8 (±0.5), 23.9 (±0.4), 9.3 (±0.6), and 5.4 (±0.6) in the frontal cortex (***P ≤ 0.001 or **P ≤ 0.01).