Table 1.
Characteristics of patients undergoing right liver resections either in one stage or as a second stage of a two-stage procedure
| Right liver resection | P-value | |||
|---|---|---|---|---|
| One-stage procedure n = 163 | Two-stage procedure n = 35 | |||
| Age (years) | 57 (46–67) | 59 (48–64) | 0.82 | |
| Gender male/female | 86/77 | 22/13 | 0.28 | |
| BMI (kg/m2) | 24 (22–27) | 23.4 (21.1–28) | 0.72 | |
| Charlson Index | 6 (2–9) | 8 (6–9) | <0.001 | |
| ASA score | 2 (2–2) | 2 (2–3) | 0.036 | |
| – ≤2 | 133 | 26 | ||
| – >2 | 30 | 9 | 0.32 | |
| Malignant disease | 125 | 31 | 0.24 | |
| Pre-operative chemotherapy | 64 | 21 | 0.025 | |
| Liver tumour | 0.008 | |||
| – None | 7 | 0 | ||
| – Primary | 74 | 9 | ||
| – Secondary | 82 | 26 | ||
| Portal vein embolization/portal vein ligation | 0 | 9/26 | – | |
| sFLR (%) | 47% (19–69%) | 47% (19–64%) | 0.96 | |
| Liver cirrhosis | 8 | 2 | 0.85 | |
| Liver steatosis | 70 | 16 | 0.79 | |
| – ≥30% | 23 | 11 | 0.006 | |
| Liver fibrosis | 33 | 10 | 0.29 | |
| AST preoperative (U/l) | 30.5 (23–41) | 37.5 (28–47) | 0.037 | |
| ALT preoperative (U/l) | 29 (19–45) | 35 (25–60) | 0.07 | |
| Bilirubin pre-operative (μmol/l) | 9 (6–13) | 8.5 (6–11) | 0.36 | |
| Creatinine pre-operative (μmol/l) | 77 (67–89) | 74 (65–79) | 0.24 | |
All results are presented in median (interquartile range).
ASA, American Society of Anesthesiologists score; AST, aspartate aminotransferase; ALT, alanine aminotransferase; BMI, body mass index; sFLR, standardized future liver remnant at the time of resection (weight of standardized total liver volume minus weight of the resected specimen).