Table 2.
Factors associated with ROP
|
|
||||||
|---|---|---|---|---|---|---|
| Iowa | Pécs | |||||
|
| ||||||
| No ROP (n=273) | ROP (n=175) | No ROP (n=144) | ROP (n=92) | |||
|
| ||||||
| Dichotomous Variables
| ||||||
| N(%) | P-value | N(%) | P-value | |||
| Female sex | 122 (44.7) | 91 (52.0) | 0.157 | 64 (44.4) | 55 (59.8) | 0.030 |
| Any hyperglycemia | 65 (23.8) | 112 (64.0) | 0.000 | 23 (16.0) | 39 (42.4) | <0.001 |
| Insulin treatment | 0 (0) | 6 (3.4) | 0.008 | 7 (4.9) | 25 (27.2) | <0.001 |
| Transfusion | 165 (60.4) | 164 (93.7) | <0.001 | 105 (72.9) | 80 (87.0) | 0.017 |
| Any infection | 50 (18.3) | 79 (45.1) | <0.001 | 95 (66.0) | 75 (81.5) | 0.014 |
| Exclusive breast feeding | 124 (45.4) | 34 (19.4) | <0.001 | 140 (97.2) | 83 (90.2) | 0.045 |
| Antenatal corticosteroids | 246 (90.1) | 147 (84.5) | 0.103 | 79 (54.9) | 38 (41.3) | 0.058 |
| Postnatal corticosteroids | 78 (28.6) | 114 (65.1) | <0.001 | 13 (9.0) | 49 (53.3) | <0.001 |
| Erythropoietin exposure | 0 (0) | 3 (1.7) | 0.115 | 68 (47.2) | 71 (77.2) | <0.001 |
| Methylxanthine exposure | 260 (95.2) | 172 (98.3) | 0.151 | 59 (41.0) | 48 (52.2) | 0.121 |
| At least 1 hemangioma | 49 (17.9) | 49 (28.0) | 0.017 | 6 (4.2) | 12 (13.0) | 0.024 |
|
| ||||||
| Continuous Variables
|
||||||
| Median (SD) | P-value | Median (SD) | P-value | |||
|
| ||||||
| Gestational age, wk | 29 (1.6) | 26 (2.1) | <0.001 | 29 (1.6) | 26 (2.0) | <0.001 |
| Birth weight, g | 1328 (340.4) | 835 (287.9) | <0.001 | 1260 (220.5) | 890 (240.9) | <0.001 |
| Number of hyperglycemic episodes | 0 (0.9) | 1 (3.5) | <0.001 | 0 (0.7) | 0 (3.2) | <0.001 |
| Highest bilirubin, mg/dl | 8.2 (2.3) | 7.3 (2.5) | <0.001 | 10.2 (3.1) | 8.1 (3.1) | <0.001 |
| Duration of oxygen therapy, d | 60 (109.7) | 219 (163.9) | <0.001 | 7 (23.1) | 54.5 (28.5) | <0.001 |
| Number of infections | 1 (0.6) | 1 (1) | 0.217 | |||