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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Surgery. 2013 Mar 13;153(6):771–778. doi: 10.1016/j.surg.2013.02.002

FIGURE 1. Our orthotopic implantation model allows for quantification of overall tumor burden and survival analysis.

FIGURE 1

(A) Representative bioluminescent images after orthotopic implantation of 1×105 4T1-luc2 cells. Bioluminescence images at 1, 8, 12 and 29 days after implantation demonstrate progressive tumor growth and metastatic spread. (B) The total tumor burden is quantified as total photons measured by bioluminescent technology as cancer progressed after implantation. (C) Kaplan-Meier survival curve of this model.