Table 1.
Combined cohort | HPFS | PHS | |
---|---|---|---|
No. of cases | 963 | 700 | 263 |
Age at blood draw, yr, mean (SD) | 64.7 (7.6) | 65.8 (7.4) | 61.7 (7.5) |
Age at diagnosis, yr, mean (SD) | 69.1 (7.3) | 68.9 (7.3) | 69.6 (7.5) |
Follow-up, yr, mean (SD) | 12.0 (4.9) | 11.6 (3.8) | 13.0 (6.8) |
Gleason score, no. (%) | |||
2–6 | 467 (54) | 353 (53) | 114 (56) |
7 | 296 (34) | 238 (36) | 58 (29) |
8–10 | 103 (12) | 73 (11) | 30 (15) |
Missing | 97 | 36 | 61 |
TNM stage, no. (%) | |||
T1/T2 | 753 (81) | 575 (85) | 178 (72) |
T3 | 118 (13) | 81 (12) | 37 (15) |
T4/N1/M1 | 55 (6) | 22 (3) | 33 (13) |
Missing | 37 | 22 | 15 |
Smoking status, no. (%) | |||
Never | 418 (45) | 310 (46) | 108 (41) |
Past | 468 (50) | 335 (50) | 133 (51) |
Current | 53 (6) | 31 (5) | 22 (8) |
Missing | 24 | 24 | 0 |
BMI, kg/m2, no. (%) | |||
<25 | 445 (46) | 293 (42) | 152 (58) |
25–29 | 435 (45) | 335 (48) | 100 (38) |
≥30 | 83 (9) | 72 (10) | 11 (4) |
Physical activity, no. (%) | |||
Low | 354 (37) | 288 (41) | 66 (25) |
Moderate | 349 (36) | 202 (29) | 147 (57) |
High | 257 (27) | 210 (30) | 47 (18) |
Missing | 3 | 0 | 3 |
Deaths, no. (%) | 421 (44) | 246 (35) | 175 (67) |
Deaths from PCa, no. (%) | 134 (14) | 72 (10) | 62 (24) |
“Lethal” PCa, no. (%) | 148 (15) | 82 (12) | 66 (25) |
BMI = body mass index; HPFS = Health Professionals Follow-up Study; PCa = prostate cancer; PHS = Physicians’ Health Study; SD = standard deviation.
Percentages may not add to 100% due to rounding.