Table 1.
The differentially expressed proteins between OA and non-OA groups identified by MALDI-TOF/TOF MS
| Spot ID | Protein name | Mr | pI | Peptides | Sequence coverage | Score | Protein expression | |
|---|---|---|---|---|---|---|---|---|
| Match | Total | |||||||
| 1031 | Apolipoprotein A-IV | 45,353 | 5.33 | 19 | 79 | 38 % | 92 | ↑ |
| 608 | Protein tyrosine phosphatase (PTP) | 135,617 | 5.91 | 27 | 83 | 24 % | 77 | ↓ |
| 640 | Dynamin | 97,545 | 7.31 | 20 | 69 | 22 % | 75 | ↑ |
| 1503 | HLA-B α chain | 21,063 | 5.97 | 21 | 60 | 47 % | 86 | ↑ |
| 1046 | Immunoglobulin heavy chain constant region | 49,433 | 6.40 | 8 | 47 | 17 % | 98 | ↑ |
| 1668 | Chain A, solution structure of the mitochondrial ribosomal protein L17 isologue | 13,656 | 9.37 | 10 | 61 | 73 % | 68 | ↑ |
| 919 | RNA binding protein, homologue 2 | 60,515 | 9.56 | 13 | 58 | 27 % | 81 | ↑ |
| 853 | A kinase (PRKA) anchor protein 4 | 75,598 | 8.48 | 17 | 71 | 29 % | 87 | ↑ |
| 1644 | Chain A, crystal structure of mutant human lysozyme | 14,606 | 9.14 | 7 | 65 | 45 % | 76 | ↓ |
| 1180 | Hakata antigen | 32,868 | 6.20 | 10 | 64 | 32 % | 74 | ↑ |
| 1441 | H-ficolin | 25,068 | 6.14 | 8 | 50 | 34 % | 66 | ↑ |
| 660 | Microtubule-associated protein 1B | 81,909 | 8.80 | 15 | 72 | 20 % | 73 | ↑ |
| 1667 | Immunoglobulin ε heavy chain variable region | 11,563 | 9.01 | 6 | 56 | 70 % | 96 | ↑ |
| 601 | Axonemal dynein light chain domain-containing protein 1 | 117,953 | 5.49 | 19 | 67 | 21 % | 75 | ↑ |
| 868 | PAB-dependent poly(A)-specific ribonuclease subunit 3 | 61,990 | 8.29 | 12 | 74 | 29 % | 84 | ↑ |
| 653 | Krüppel-like zinc finger protein (KLF) | 75,080 | 9.44 | 10 | 45 | 20 % | 82 | ↑ |
| 1421 | Calumenin isoform 5 | 26,847 | 4.61 | 6 | 40 | 31 % | 70 | ↓ |
| 1403 | Scavenger receptor | 28,852 | 6.65 | 8 | 55 | 29 % | 74 | ↑ |
| 1475 | Apolipoprotein A-I | 23,389 | 5.55 | 7 | 31 | 35 % | 127 | ↑ |
| 1134 | Secernin | 41,237 | 5.80 | 7 | 48 | 21 % | 69 | ↓ |
| 1720 | β-catenin-interacting protein 1 | 9,165 | 5.33 | 5 | 36 | 59 % | 66 | ↓ |
| 1674 | HLA-DR | 10,953 | 6.08 | 4 | 54 | 43 % | 87 | ↑ |
| 912 | HSPA9 protein | 73,808 | 6.04 | 16 | 57 | 34 % | 82 | ↑ |
| 1501 | Ribosomal protein L27a (RPL27a) | 3,706 | 9.69 | 3 | 21 | 82 % | 75 | ↑ |
| 1089 | Nucleolar phosphoprotein p130 (p130) | 73,677 | 9.48 | 7 | 39 | 16 % | 85 | ↑ |
The spot ID refers to the number used in 2-DE to indicate the location of the protein. The protein score is −10 × Log(P), where P is the probability that the observed match is a random event. Protein scores greater than 66 are significant (p < 0.05). “↑”indicates the up-regulated proteins in OA. “↓”indicates the down-regulated proteins in OA