Table I. Summary of risk factors for AML.

Generally accepted risk factors	Suggestive of increased risk	Suggestive of decreased risk	Limited evidence
Down syndrome	Older maternal age	Long term breastfeeding	Paternal exposure to benzene
Fanconi anemia	Increasing birth order		Parental smoking
Familial monosomy 7	Prior fetal loss		Maternal exposure to benzene
Ataxia telangiectasia	Maternal alcohol use		Maternal use of antibiotics
Shwachman-Diamond syndrome	Maternal exposure to pesticides		Maternal dietary consumption of DNA topoisomerase II inhibitors (infant)
Bloom syndrome	High birth weight
Ionizing radiation in utero	Low birth weight