Table 1.

Genes associated with alcohol dependence in COGA

Study	Gene	Replication
Edenberg et al., 2004	GABRA2	Covault et al., 2004; Fehr et al., 2006; Lappalainen et al., 2005; Soyka et al., 2008; Enoch et al., 2006; Drgon et al., 2006
Dick et al., 2004	GABRB3 and GABRG3	Noble et al., 1998; Song et al., 2003 GABRB3
Wang et al., 2004	CHRM2	Luo et al., 2005a
Hinrichs et al., 2006	TAS2R16
Wang et al., 2009	CHRNA5	Saccone et al., 2007
Xuei et al., 2006	PDYN and OPRK1	Williams et al., 2007; Gerra et al., 2007
Edenberg et al., 2006	ADH genes: ADH4, ADH1A, ADH1B	Luo et al., 2005b; Guindalini et al., 2005
Edenberg et al., 2008	NFKB1
Foroud et al., 2008	TACR3
Dick et al., 2008	ACN9
Dick et al., 2007b	ANKK1/DRD2