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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Clin Endocrinol (Oxf). 2013 May 20;79(3):429–436. doi: 10.1111/cen.12163

Table 3.

Association of parathyroid hormone and calcium with measures of arterial function

Mean ± SD Model PTH < 65 pg/ml PTH ≥ 65 pg/ml
Calcium < 10.2 mg/dL Calcium ≥ 10.2 mg/dL

Beta Beta (95% CI) Beta (95% CI)

FMD, percent change (N = 3341) 4.40 ± 2.81 1 0 (Reference) −0.28 (−0.57, 0.02) −0.52 (−1.18, 0.15)
2 0 (Reference) −0.28 (−0.59, 0.03) −0.54 (−1.22, 0.13)

Aortic PP, mmHg (N = 6042) 53.11 ± 14.84 1 0 (Reference) 2.34 (1.24, 3.45)* 3.77 (0.79, 6.76)*
2 0 (Reference) 1.82 (0.68, 2.95)* 3.37 (0.28, 6.46)*

LAE, ml/mmHg X 10 (N = 6083) 13.34 ± 5.61 1 0 (Reference) −0.46 (−0.84, −0.07)* −1.03 (−2.07, 0.01)
2 0 (Reference) −0.50 (−0.90, −0.11)* −1.14 (−2.20, −0.07)*

SAE, ml/mmHg X 100 (N = 6083) 4.49 ± 2.83 1 0 (Reference) −0.02 (−0.22, 0.17) −0.21 (−0.72, 0.3)
2 0 (Reference) −0.11 (−0.30, 0.08) −0.34 (−0.86, 0.18)

Model 1: Adjusted for age, gender, race, and study site.

Model 2: Adjusted for age, gender, race, study site, diabetes, smoking, BMI, LDL, lipid lower medications, eGFR, and 25(OH)D.

Beta and 95% confidence interval are differences in mean measure of arterial function (units unique to each outcome) comparing high parathyroid hormone (> 65 pg/ml) categories to normal parathyroid hormone (< 65 pg/ml) category. PTH, parathyroid hormone, SD, standard deviation, CI, confidence interval, FMD, flow-mediated dilation, Aortic PP, aortic pulse pressure, LAE, large artery elasticity, SAE, small artery elasticity.

*

p < 0.05