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. Author manuscript; available in PMC: 2013 May 26.
Published in final edited form as: Virology. 2010 Jul 1;405(1):234–242. doi: 10.1016/j.virol.2010.06.001

Fig. 2.

Fig. 2

Valproic acid inhibits CD8+ T-lymphocyte noncytolytic suppression at different levels of HIV-1 gene expression. CD4+ T-lymphocytes were infected with four different amounts of HIV-1NL4-3 pseudotyped virus to generate a titration of HIV-1 replication from 1.6×106 to 0.08×106 relative light units. JR-HVS CD8+ T-lymphocytes were cultured in direct contact at a 2:1 effector to target ratio with CD4+ T-lymphocytes infected with each of the different amounts of HIV-1NL4-3 pseudotyped virus. Valproic acid was added to the growth media in increasing concentrations. HIV-1 replication in the CD8+ T-lymphocyte co-culture is shown as the percentage of replication in the infected CD4+ T cells cultured alone. Mean and standard error of duplicate experiments are shown.