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Severe leukocytosis was observed only after open cholecystectomy, but not after aparoscopic cholecystectomy, mostly due to an increment of neutrophils on day 1 and 3. Regarding Neutrophilis values, the difference between baseline values and post-operative values were significant in both groups (using the Friedman test, aP < 0.05). LC: Laparoscopic cholecystectomy; OC: Open cholecystectomy.
