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. 2013 Apr 16;108(9):1810–1816. doi: 10.1038/bjc.2013.123

Figure 4.

Figure 4

Predictive value of modelled kinetic parameters.

(A) Predictions of MTX resistance offered by two modelled kinetic parameters K (AUC=0.69, 95% CI=0.64–0.74) and hCGres (AUC=0.94, 95% CI=0.91–0.96). (B) Predictive values of hCGres (>20.44 IU l−1: AUC=0.86, 95% CI=0.83–0.89) against previously reported predictors: hCG values on week 7 (>737 IU l−1: AUC=0.66; 95% CI=0.62–0.70; >520.24 IU l−1: AUC=0.69, 95% CI=0.65–0.74; >500 IU l−1: AUC=0.70, 95% CI=0.65–0.74) and the WHO–FIGO score (AUC=0.66, 95% CI=0.62–0.70). (C) Predictive value of modelled hCGres categorised by 20.44 cut-off value regarding MTX failure-free survival. Three-year MTX failure-free survival=89.7% vs 21.8%, hCGres <0.0001.