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. 2013 Apr 6;177(11):1236–1245. doi: 10.1093/aje/kws378

Table 2.

Factors That Are Varied in the Analysis

Analysis Variables Description Calculation Rangea
Maximum R0 Reproduction number in immunologically naive population c0 4–20 (26)
OPV transmissibility Transmissibility relative to WPV (%) ɛ/κ 0%–20% (26)
Susceptibility waning rate Exponential waningb 0.04, 0.07, and 0.1/yearc,d
φj Effective vaccination rates in children (0–5 years of age) 0–3/year (1, 23)

Abbreviations: OPV, oral polio vaccine; WPV, wild poliovirus.

a Upper and lower bounds were selected as biologically plausible limits.

c Waning rate values are not well defined and were, therefore, chosen to examine the impact of waning on the dynamics for wide-ranging outcomes. Additional values are explored in Web Appendices 5.1 and 5.3.

d The susceptibility waning rates, 0.04, 0.07, and 0.1 per year, correspond to reaching 50% susceptibility after 17, 10, and 7 years, respectively.