Table 2.

Type of stressor or stressor-like stimuli that induce recruitment or up-regulation of Cav3 (T-type) channels in different cells and tissues

Stressors	Cell type, tissue	Cav3 type	Reference
Chronic hypoxia	PC12	Cav3.2	Del Toro et al., 2003
Long-term β-AR exposure	Adult RCCs	Cav3.2	Novara et al., 2004
Chronic hypoxia	Adult RCCs	Cav3.2	Carabelli et al., 2007b
Adrenal gland splanchnic denervation	Neonatal RCCs	Cav3.2	Levitsky & Lopez-Barneo, 2009
Intermittent hypoxia	Neonatal RCCs	Cav3.1, Cav3.2	Souvannakitti et al., 2010
Acute high-frequency sympathetic stimulation	Adult MCCs (adrenal gland slices)	Cav3.2	Hill et al., 2011
Acute PACAP-mediated stimulation	Adult MCCs (adrenal gland slices)	Cav3.2	Kuri et al., 2009
Long-term ACTH exposure	Bovine zona fasciculata cells	Cav3.2	Barbara & Takeda, 1995 Liu et al., 2010
Long-term VIP exposure	Bovine zona fasciculata cells	Cav3 (?)	Barbara & Takeda, 1995
Chronic hypoxia	Neonatal rat ventricular myocytes	Cav3.2	Pluteanu & Cribbs, 2009
Pulmonary hypertension	Rat ventricular myocytes	Cav3 (?)	Takebayashi et al., 2006
Cardiomyopathic heart	Hamster ventricular myocytes	Cav3 (?)	Sen & Smith, 1994
Hypertrophic heart	Feline ventricular myocytes	Cav3 (?)	Nuss & Hauser, 1993
Long-term aldosterone exposure	Neonatal rat ventricular myocytes	Cav3.2	Lalevée et al., 2005
Long-term aldosterone exposure	Human adrenocarcinoma	Cav3.2	Lesouhaitier et al., 2001
Cell proliferation	Human cancer cells	Cav3.1, Cav3.2	Mariot et al., 2002 Panner & Wurster, 2006
Diabetic neuropathic pain	Rat hindpaws sensory neurons	Cav3.2	Jagodic et al., 2007
Chronic visceral pain	Rat colonic sensory neurons	Cav3.2	Marger et al., 2011