Fig. 2.

Expression of mRNA for Nrf-2 and Nrf2 target genes in choroid plexuses after 50 min hypoxia-ischemia (HI50). The mRNA expression for Nrf2 and its gene targets were analyzed in choroid plexuses from the ipsilateral (left) and contralateral (right) ventricles at 2-, 6- and 24-h after 50 min HI (HI50) at PND9. Nrf2 gene expression in plexuses from ipsilateral side was significantly higher at 2 h but not at 6- and 24-h after HI in comparison to the plexuses from the contralateral hemisphere (a). All Nrf2 target genes showed similar temporal changes after HI50 with the highest upregulation at 2 h, less upregulation at 6 h and normal levels at 24 h (b–d). Data are shown as fold change between left and right ventricular (left/right) plexus±SEM, ^*p≤0.05, ^**p≤0.01