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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: J Inherit Metab Dis. 2012 Oct 30;36(3):479–490. doi: 10.1007/s10545-012-9551-5

Fig. 3.

Fig. 3

Expression of mRNA for Nrf-2 and Nrf2 target genes in choroid plexuses after LPS/hypoxia-ischemia (LPS/HI). The mRNA expression for Nrf2 and its gene targets were analyzed in choroid plexuses from the ipsilateral (left) and contralateral (right) ventricles at 2 h after saline or LPS administration combined with 20 min HI at PND9 (HI20 and LPS/HI, respectively). Nrf2 gene expression in plexuses from left side was significantly higher after saline exposure but not after LPS (a). Gclm was not altered by saline while it was significantly down-regulated in the left choroid plexus after LPS (c). Gclc (b) and HO-1 (d) genes were upregulated in both saline and LPS injected animals. No significant relevance between two groups. Data are shown as fold change between left and right ventricular (left/right) plexus±SEM, *p≤0.05, **p≤0.01