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. 2013 Mar;14(2):97–110. doi: 10.2174/13892037112139990033

Fig. (5).

Fig. (5)

Main steps in the fusion of endocytic vesicles. First, the HOPs complex, RABs and other proteins are recruited to the target vesicle in order to allow tethering with the other vesicle. Subsequently, v- and t-SNAREs interact to allow the appropriate docking of the two opposite membranes. Ca2+ release from the target vesicle occurs at this stage to facilitate the blending of the two membranes. See text for further details.