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. Author manuscript; available in PMC: 2014 Feb 21.
Published in final edited form as: Cell Rep. 2013 Feb 14;3(2):359–370. doi: 10.1016/j.celrep.2013.01.024

Figure 5. ATM is involved in ensuring mono-allelic RAG-mediated cleavage on Tcra alleles.

Figure 5

(A) Frequency of γ-H2AX association on total (left) or paired (right) Tcra alleles in WT and Atm−/− DP cells. p values were calculated using a two-tail Fisher exact test.

(B) Confocal sections show examples of simultaneous bi-allelic γ-H2AX association on unpaired (top) and paired (bottom) Tcra alleles in Atm−/− DP cells. 3’α in red, 5’α in green and γ-H2AX in white. Scale bars = 1 µm.

See also Figure S4 and Table S5 for details and full statistical analyses.