Table 2.
National Cardiovascular Research Infrastruture Data Elements
| Element Name |
Source | Element Name |
Source | Element Name |
Source |
|---|---|---|---|---|---|
| Personal history | |||||
| Hypertension | ACC/AHA CV EHR | Transient Ischemic Attack | ACC/AHA CV EHR | Hemodynamic Instability assoc. with Ventricular Tachycardia | NCDR (ICD) |
| Diabetes Mellitus | ACC/AHA CV EHR | Ischemic Stroke | ACC/AHA CV EHR | ICD | NCDR (ICD) |
| Diabetes Therapy | NCDR (ACTION-GWTG) | Hemorrhagic Stroke | ACC/AHA ACS | Initial ICD reason is Cardiac Arrest/arrhythmia Etiology Unknown | NCDR (ICD) |
| Dyslipidemia | ACC/AHA CV EHR | Undetermined Stroke | New | Initial ICD reason is Not Documented | NCDR (ICD) |
| Tobacco Use | ACC/AHA CV EHR | Syndromes at risk for sudden death | NCDR (ICD) | Initial ICD reason is Spontaneous Sustained VT | NCDR (ICD) |
| Tobacco Use-Smoked Tobacco Type | New | Sudden death syndrome type | NCDR (ICD) | Initial ICD reason is Syncope with High Risk Characteristics | NCDR (ICD) |
| Smokeless Tobacco | New | Syncope | ACC/AHA CV EHR | Initial ICD reason is Syncope with Inducible VT | NCDR (ICD) |
| Heart Failure | STS Adult Cardiac | Syncope Date | ACC/AHA CV EHR | Initial ICD reason is Ventricular Fibrillation | NCDR (ICD) |
| Heart Failure Hospital Timeframe | NCDR (ICD) | Syncope-Frequency of Episodes | ACC/AHA CV EHR | Structural Abnormality Type - Amyloidosis | NCDR (ICD) |
| CHF Hospitalization | NCDR (ICD) | Syncope-Number of Episodes | ACC/AHA CV EHR | Structural Abnormality Type - Atrial Septal Defect | NCDR (ICD) |
| Prior cardiac transplant | NCDR (ICD) | Sleep Apnea | ACC/AHA EP | Structural Abnormality Type - Chagas Disease | NCDR (ICD) |
| Heart transplant waiting list | NCDR (ICD) | Sleep Apnea-Sleep Study Diagnosis | New | Structural Abnormality Type - Common Ventricle | NCDR (ICD) |
| NYHA Class | ACC/AHA CV EHR | Aorta Disease | ACC/AHA CV EHR | Structural Abnormality-Type - Ebstein's Anomaly | NCDR (ICD) |
| Chronic Kidney Disease | ACC/AHA CV EHR | Peripheral Arterial Disease | ACC/AHA CV EHR | Structural Abnormality Type - Giant Cell Myocarditis | NCDR (ICD) |
| Dialysis | ACC/AHA CV EHR | Renal Artery Disease | ACC/AHA CV EHR | Structural Abnormality Type - Hypertrophic Cardiomyopathy | NCDR (ICD) |
| Chronic Lung Disease | ACC/AHA CV EHR | Deep Venous Thrombosis | ACC/AHA CV EHR | Structural Abnormality Type - Left Ventricuar Aneurysm | NCDR (ICD) |
| Chronic Lung Disease-Home Oxygen Therapy | New | Venous thromboembolism | ACC/AHA CV EHR | Structural Abnormality Type-LV Non-compaction Syndrome | NCDR (ICD) |
| Coronary artery disease | ACC/AHA CV EHR | Pulmonary Embolism | ACC/AHA CV EHR | Structural Abnormality Type - Other | NCDR (ICD) |
| One epicardial artery > = 70% confirmed by angiography | NCDR (ICD) | Primary Valvular Disease | ACC/AHA CV EHR | Structural Abnormality Type - Right Ventricular Dysplasia (ARVD) | NCDR (ICD) |
| Myocardial Infarction | ACC/AHA CV EHR | Prior Valve Surgery/Procedure | NCDR (CathPCI) | Structural Abnormality Type - Sarcoidosis | NCDR (ICD) |
| Myocardial Infarction timeframe | NCDR (ICD) | Sinus Node Function | ACC/AHA EP | Structural Abnormality Type - Transposition of Great Vessels | NCDR (ICD) |
| PCI | NCDR (CathPCI) | Permanent Pacemaker | NCDR (ICD) | Structural Abnormality Type - Tetralogy of Fallot | NCDR (ICD) |
| CABG Surgery | NCDR (CathPCI) | Atrial arrhythmias | ACC/AHA CV EHR | Structural Abnormality Type - Ventricular Septal Defect | NCDR (ICD) |
| Cardiac Arrest | ACC/AHA CV EHR | Atrial Fibrillation | NCDR (ICD) | Depression | ACC/AHA CV EHR |
| Cardiac Arrest Date | ACC/AHA CV EHR | Atrial Fibrillation Classification | NCDR (ICD) | HIV Infection | ACC/AHA CV EHR |
| Cardiac Arrest Due to Arrhythmia | NCDR (ICD) | Atrial Flutter | NCDR (ICD) | Illicit Drug Use | ACC/AHA CV EHR |
| Previous ICD Implant site | NCDR (ICD) | Bradycardia arrest | NCDR (ICD) | Illicit Drug Use Type-Cocaine Use | NCDR (ICD) |
| Previous ICD reason | NCDR (ICD) | Ventricular arrhythmias | ACC/AHA CV EHR | Patient Life Expectancy of > = 1 year | NCDR (ICD) |
| Previous ICD type | NCDR (ICD) | Ventricular Tachycardia | NCDR (ICD) | Clinical Trial | NCDR (ICD) |
| Cardiogenic Shock | STS Adult Cardiac | Ventricular Tachycardia Type | NCDR (ICD) | ||
| Cerebral Artery Disease | ACC/AHA CV EHR | VT/VF Arrest | NCDR (ICD) | ||
| Family history | |||||
| Coronary artery disease | ACC/AHA CV EHR | Sudden Cardiac Death | ACC/AHA CV EHR | ||
| Physical exam | |||||
| Height | ACC/AHA CV EHR | Heart Rate | ACC/AHA CV EHR | Anginal classification | ACC/AHA CV EHR |
| Weight | ACC/AHA CV EHR | Heart Rate Date/Time | ACC/AHA CV EHR | Anginal Classification Date | ACC/AHA CV EHR |
| Systolic Blood Pressure | ACC/AHA CV EHR | Waist Circumferance | ACC/AHA CV EHR | Killip Class | ACC/AHA ACS |
| Diastolic Blood Pressure | ACC/AHA CV EHR | Chest Pain: Angina or Anginal Equivalent | ACC/AHA CV EHR | New York Heart Association Class | ACC/AHA CV EHR |
| Laboratory values | |||||
| Blood Urea Nitrogen | CDISC-CDASH | Total Cholesterol | CDISC-CDASH | Sodium | CDISC-CDASH |
| Creatinine | CDISC-CDASH | LDL Cholesterol | CDISC-CDASH | Potassium | CDISC-CDASH |
| Hematocrit | CDISC-CDASH | HDL Cholesterol | CDISC-CDASH | Creatine Kinase (CK) | CDISC-CDASH |
| Hemoglobin | CDISC-CDASH | Triglycerides | CDISC-CDASH | Creatine Kinase MB (CK-MB) | CDISC-CDASH |
| Glucose, any | CDISC-CDASH | Brain Naturetic Peptide (BNP) | CDISC-CDASH | Troponin | CDISC-CDASH |
| Glucose, fasting | ACC/AHA CV EHR | NT-proBNP | CDISC-CDASH | Troponin I | CDISC-CDASH |
| Hemoglobin A1c | CDISC-CDASH | Prothrombin Intl. Normalized Ratio (INR) | CDISC-CDASH | Troponin T | CDISC-CDASH |
| Diagnostic Procedures | |||||
| Cardiac diagnostic procedure | ACC/AHA CV EHR | Cardiac Rhythm-Sinus Rhythm | NCDR (ICD) | PR Interval | NCDR (ICD) |
| Date of cardiac diagnostic procedure | ACC/AHA CV EHR | Cardiac Rhythm-Atrial Tachycardia | NCDR (ICD) | PR Interval not obtainable | NCDR (ICD) |
| 12 Lead ECG | NCDR (ICD) | Cardiac Rhythm-Junctional | NCDR (ICD) | Cardiac Rhythm-Second Degree Heart Block | NCDR (ICD) |
| 12 Lead ECG Date/Time | NCDR (ICD) | Cardiac Rhythm-Idioventricular | NCDR (ICD) | Cardiac Rhythm-Third Degree Heart Block | NCDR (ICD) |
| ECG (any) | NCDR (ICD) | Cardiac Rhythm-Afib/Flutter | NCDR (ICD) | Abnormal Intraventricular Conduction | NCDR (ICD) |
| ECG (any) Date/Time | NCDR (ICD) | Cardiac Rhythm-Paced | NCDR (ICD) | Abnormal Intraventricular Conduction Type - Delay, Nonspecific | NCDR (ICD) |
| ECG Timing with STEMI or STEMI Equivalent | NCDR (ACTION GWTG) | Pacing Type | NCDR (ICD) | Abnormal Intraventricular Conduction Type - Left Anterior Fascicular Block | NCDR (ICD) |
| ECG Findings for NSTEMI | NCDR (ACTION-GWTG) | Underlying Atrial Rhythm | NCDR (ICD) | Abnormal Intraventricular Conduction Type - Left Posterior Fascicular Block | NCDR (ICD) |
| ECG Findings for STEMI | NCDR (ACTION-GWTG) | Only Ventricular Paced QRS Complexes | NCDR (ICD) | Abnormal Intraventricular Conduction Type - Left Bundle Branch Block | NCDR (ICD) |
| Electrophysiology Study | NCDR (ICD) | QRS Duration (Non-ventricular Paced Complexes) | NCDR (ICD) | Abnormal Intraventricular Conduction Type - Right Bundle Branch Block | NCDR (ICD) |
| Ventricular Arrhythmias Induced | NCDR (ICD) | Ventricular Paced QRS Duration | NCDR (ICD) | Abnormal Intraventricular Conduction Type - Ventricular Paced Rhythm | NCDR (ICD) |
| Non-Invasive Stress Testing | NCDR (ACTION-GWTG) | Stress Echo Imaging Results | NCDR (CathPCI) | Cardiac CTA | NCDR (CathPCI) |
| Stress Test Result | ACC/AHA CV EHR | Risk/Extent of Ischemia (Stress Echo) | NCDR (CathPCI) | Cardiac CTA Results | NCDR (CathPCI) |
| Exercise Stress Test Results | NCDR (CathPCI) | Stress Test with CMR Imaging Results | NCDR (CathPCI) | Pre-test probability of coronary artery disease | ACC/AHA CV EHR |
| Spect/MPI Imaging Results | NCDR (CathPCI) | Risk/Extent of Ischemia (Stress Test with CMR) | NCDR (CathPCI) | ||
| Risk/Extent of Ischemia (Spect/MPI) | NCDR (CathPCI) | ||||
| Left Ventricular Ejection Fraction (qualitative) | ACC/AHA CV EHR | Left atrium size (quantitative) | ACC/AHA CV EHR | ||
| Left Ventricular Ejection Fraction (quantitative) | ACC/AHA CV EHR | Aortic valve stenosis severity | ACC/AHA CV EHR | Mitral valve stenosis severity | ACC/AHA CV EHR |
| Left ventricle size, end-diastole (quantitative) | ACC/AHA CV EHR | Aortic valve area | ACC/AHA CV EHR | Mitral valve area | ACC/AHA CV EHR |
| Left ventricle size, end-systole (quantitative) | ACC/AHA CV EHR | Aortic valve regurgitation severity | ACC/AHA CV EHR | Mitral valve regurgitation severity | ACC/AHA CV EHR |
| Diagnostic Catheterization | NCDR (CathPCI) | Reason for Diagnostic Catheterization_Cardiac Transplantation | NCDR (CathPCI) | Intravascular Ultrasound (IVUS) | NCDR (CathPCI) |
| Diagnostic Catheterization Status | NCDR (CathPCI) | Reason for Diagnostic Catheterization_Cardiac Transplant Evaluation Type | NCDR (CathPCI) | Fractional Flow Reserve Reserve Ratio | NCDR (CathPCI) |
| Left Heart Catheterization | NCDR (CathPCI) | Reason for Diagnostic Catheterization_Cardiomyopathy or Left ventricular systolic dysfunction evaluation | NCDR (CathPCI) | Fractional Flow Reserve Ratio | NCDR (CathPCI) |
| Diagnostic Coronary Angiography | NCDR (CathPCI) | Reason for Diagnostic Catheterization_Pre-operative evaluation for non-cardiovascular surgery | NCDR (CathPCI) | ||
| Coronary Anatomy Dominance | NCDR (CathPCI) | ||||
| Coronary artery: number of diseased vessels (excludes left main disease) | ACC/AHA CV EHR | ||||
| Stenosis location | NCDR (CathPCI) | ||||
| Stenosis severity | NCDR (CathPCI) | ||||
| Therapeutic Procedures | |||||
| Cardiac Therapeutic Procedure | ACC/AHA CV EHR | Percutaneous Coronary Intervention | NCDR (CathPCI) | Primary reason reperfusion therapy not indicated-Urgent Cardiac Surgery | NCDR (ACTION-GWTG) |
| Date of Cardiac Therapeutic Procedure | ACC/AHA CV EHR | PCI Indication | NCDR (CathPCI) | Non-system reason for Delay in PCI | NCDR (CathPCI) |
| Coronary Artery Bypass Graft Surgery | NCDR (CathPCI) | PCI Status | NCDR (CathPCI) | Culprit Lesion | NCDR (CathPCI) |
| Coronary Bypass Graft Surgery Status | NCDR (CathPCI) | Coronary lesions treated | NCDR (CathPCI) | Pre-Procedure TIMI Flow | NCDR (CathPCI) |
| Coronary graft anastomoses | ACC/AHA CV EHR | Lesion Complexity Description | NCDR (CathPCI) | Post-Procedure TIMI Flow | NCDR (CathPCI) |
| Stent Placed in affected coronary artery | NCDR (CathPCI) | Bifurcation Lesion | NCDR (CathPCI) | Percent Stenosis | NCDR (CathPCI) |
| Stent placed in previous lesion | NCDR (CathPCI) | Chronic Total Occlusion | NCDR (CathPCI) | Lesion Length | NCDR (CathPCI) |
| Stent Placed in Previous PCI | NCDR (CathPCI) | Lesion in Graft | NCDR (CathPCI) | Guidewire Across Lesion | NCDR (CathPCI) |
| Stent Type | NCDR (CathPCI) | Location in Graft | NCDR (CathPCI) | Intracoronary Device Used | NCDR (CathPCI) |
| Previously Treated Lesion | NCDR (CathPCI) | Intra-aortic Balloon Pump (IABP) | NCDR (CathPCI) | Device Deployment | NCDR (ICD) |
| Previous treatment type_Stent | NCDR (CathPCI) | Intra-aortic Balloon Pump (IABP) Timing | NCDR (CathPCI) | Device Diameter | NCDR (ICD) |
| Reason for current treatment of previously treated lesion_In-stent Restenosis | NCDR (CathPCI) | Mechanical Ventricular Support-Other | NCDR (CathPCI) | Device Length | NCDR (CathPCI) |
| Reason for current treatment of previously treated lesion_in-stent Thrombus | NCDR (CathPCI) | Mechanical Ventricular Support–Other, Timing | NCDR (CathPCI) | Contrast Volume | NCDR (CathPCI) |
| Arterial Access Site | NCDR (CathPCI) | Fluoroscopy Dose | NCDR (CathPCI) | ||
| Arterial Access Closure Method | NCDR (CathPCI) | Fluoroscopy Time | NCDR (CathPCI) | ||
| Electrophysiology Procedure | NCDR (ICD) | VT Ablation Performed | NCDR (ICD) | ||
| ICD | NCDR (ICD) | ATP or Shock Therapy Appropriate | NCDR (ICD) | Lead Abnormality_Oversensing with Shock or ATP | NCDR (ICD) |
| ICD Procedure Indication | NCDR (ICD) | ATP or Shock Therapy Delivered | NCDR (ICD) | Lead Abnormality_Oversensing with out Shock or ATP | NCDR (ICD) |
| Device Implanted | NCDR (ICD) | ATP Therapy Successful | NCDR (ICD) | Lead Abnormality_Defibrillation Issues | NCDR (ICD) |
| Device Explanted | NCDR (ICD) | Shock Therapy Successful | NCDR (ICD) | Lead Abnormality_Extracardiac Stimulation | NCDR (ICD) |
| Device Manufacturer | NCDR (ICD) | CS/LV Lead Successful | NCDR (ICD) | Lead Abnormality_Failure to Capture | NCDR (ICD) |
| Device Model Name | NCDR (ICD) | Reason CS/LV Lead Not Implanted | NCDR (ICD) | Lead Abnormality_Failure to Pace | NCDR (ICD) |
| Device Model Number | NCDR (ICD) | Battery Voltage | NCDR (ICD) | Lead Abnormality_Oversensing | NCDR (ICD) |
| Device Returned to Manufacturer | NCDR (ICD) | Conductor Failure | NCDR (ICD) | Lead Abnormality_Undersensing | NCDR (ICD) |
| Device Serial Number | NCDR (ICD) | Defribillation Threshold/Lowest Energy Tested | NCDR (ICD) | Lead Dislodgement Requiring Reposition/Reoperation | NCDR (ICD) |
| Lead Returned to Manufacturer | NCDR (ICD) | Upper Limit of Vulnerability | NCDR (ICD) | Lead Erosion | NCDR (ICD) |
| Manufacturer Advisory/Recall | NCDR (ICD) | Failed to Shock with Inadequate DFT Safety Margin | NCDR (ICD) | Lead Infection | NCDR (ICD) |
| Non-lead Related Medical/Surgical Procedure | NCDR (ICD) | Faulty Connector Header | NCDR (ICD) | Lead Perforation | NCDR (ICD) |
| Reason for Malfunction | NCDR (ICD) | Lead Location | NCDR (ICD) | ||
| Reason(s) for Reimplant | NCDR (ICD) | Existing Lead Dislodgement | NCDR (ICD) | ||
| Existing Lead Status | NCDR (ICD) | ||||
| Existing Lead Function | NCDR (ICD) | ||||
| Clinical/Adverse Events | |||||
| Significant Coronary Dissection | NCDR (CathPCI) | Myocardial infarction | NCDR (CathPCI) | Pneumothorax | NCDR (ICD) |
| Coronary Artery Perforation | NCDR (CathPCI) | Urgent cardiac surgery | NCDR (CathPCI) | Hemothorax | NCDR (ICD) |
| Coronary Thrombus | NCDR (CathPCI) | Cardiac Tamponade | NCDR (CathPCI) | Peripheral Embolus | NCDR (ICD) |
| Coronary Venous Dissection | NCDR (ICD) | Luminal/Carotid Thrombus | NCDR (CARE) | Peripheral Nerve Injury | NCDR (ICD) |
| Cardiac Valve Injury | NCDR (ICD) | Venous Obstruction | NCDR (ICD) | Infection Requiring Antibiotics | NCDR (ICD) |
| Chamber Thrombus | ACC/AHA EP | Hematoma at Access Site | NCDR (CathPCI) | Set Screw Problem | NCDR (ICD) |
| Conduction Block | NCDR (ICD) | Hematoma Size | NCDR (CathPCI) | Drug Reaction/Serious Substance-related Adverse Event | NQF-QDM |
| Cardiac Perforation | NCDR (ICD) | Hematoma Requiring Re-op | NCDR (CathPCI) | Drug/Substance Allergy | NQF-QDM |
| Pericardial Effusion | NCDR (ICD) | Red blood cell or whole blood transfusion | NCDR (CathPCI) | ||
| Medications | |||||
| At Home Medications | New | Medication Timepoint | CDISC-CDASH | Prophylactic Antibiotics Within 1 hour of procedure start time | NCDR (ICD) |
| Aspirin in First 24 hours | NCDR (ACTION-GWTG) | Medications Held or Discontinued | New | Diuretic | ACC/AHA CV EHR |
| Clopidogrel in First 24 hours | NCDR (ACTION-GWTG) | Blinded | New | Direct renin inhibitor | ACC/AHA CV EHR |
| Prasugrel in First 24 hours | NCDR (ACTION-GWTG) | Contraindication | New | Alpha blocker | ACC/AHA CV EHR |
| Ticlipodine in First 24 hours | NCDR (ACTION-GWTG) | Anticoagulant | ACC/AHA CV EHR | Steroid, systemic | ACC/AHA CV EHR |
| Beta Blocker in First 24 hours | NCDR (ACTION-GWTG) | Cyclo-oxygenase 2 inhibitor | ACC/AHA CV EHR | Nonsteroidal anti-inflammatory | ACC/AHA CV EHR |
| ACE Inhibitor in First 24 hours | NCDR (ACTION-GWTG) | P2Y12 inhibitor | ACC/AHA CV EHR | ||
| Angiotensin Receptor Blocker in First 24 hours | NCDR (ACTION-GWTG) | Beta-Blockers | CDISC-CDASH | ||
| Statin in First 24 hours | NCDR (ACTION-GWTG) | GP IIb/IIIa Inhibitor | CDISC-CDASH | ||
| Non-Statin Lipid Lowering in First 24 hours | NCDR (ACTION-GWTG) | Lipid Lowering Statin Medications | CDISC-CDASH | ||
| Aldosterone Blocking Agent in First 24 hours | NCDR (Action-GWTG) | Non Statin Lipid Lowering Medications | CDISC-CDASH | ||
| Discharge | |||||
| Vital Status | NCDR (CathPCI) | Dietary Counseling | NCDR (ACTION-GWTG) | Transfer for Procedure | NCDR (CathPCI) |
| Comfort Measures | NCDR (ACTION-GWTG) | Exercise Counseling | NCDR (ACTION-GWTG) | Transfer for Procedure Location | NCDR (CathPCI) |
| CMS Comfort Measures Timing | NCDR (ACTION-GWTG) | Smoking Counseling | NCDR (ACTION-GWTG) | ||
| CMS Discharge Disposition | NCDR (ACTION-GWTG) | Cardiac Rehabilitation Referral | NCDR (ACTION-GWTG) | ||
| Outcomes | |||||
| Death | ACC/AHA CV EHR | ||||
| Date of death | ACC/AHA CV EHR | ||||
| Cause of death | NCDR (CathPCI) | ||||
| Cardiac death | ACC/AHA CAD | ||||
| Death During Procedure | NCDR (CathPCI) | ||||
ACC/AHA ACS = ACC/AHA Acute Coronary Syndromes Data Standard (Ref. 7).
ACC/AHA CV EHR = ACC/AHA Cardiovascular Vocabulary for Electronic Health Records Data Standard. (Ref. 4).
ACC/AHA CAD = ACC/AHA Coronary Artery Disease Data Standard (Ref. 9).
CDISC-CDASH = Clinical Data Interchange Standards Consortium - Clinical Data Acquisition Standards Harmonization (Ref. 10).
STS Adult Cardiac = Society of Thoracic Surgeons Adult Cardiac Surgery Data Registry (Ref. 8).
NCDR (ACTION-GWTG) = NCDR ACTION-GWTG Registry (see text and Table 1).
NCDR (CARE) = NCDR CARE Registry (see text and Table 1).
NCDR (CathPCI) = NCDR CathPCI Registry (see text and Table 1).
NCDR (ICD) = NCDR ICD Registry (see text and Table 1).
NQF-QDM = National Quality Forum-Quality Data Model (Ref. 11).