Table 1.

DEFB1 SNP-allele frequencies in various groups of samples

Region	SNP	f (Allele)	Group of samples†
			CFAR		MACS	Coriell
			White(n = 37)	Black (n = 65)	(n = 39)	NE (n = 10)	AfSS (n = 9)	Af-Am (n = 10)	CHN (n = 10)	MEX (n = 7)
Exon-1	-610G/A	f (G)	0.69	0.77	0.74	0.75	0.78	0.75	0.45	0.57
		f (A)	0.31	0.23	0.26	0.25	0.22	0.25	0.55	0.43
	-390T/A	f (T)	0.61	0.46	0.72	0.70	0.50	0.40	0.40	0.50
		f (A)	0.39	0.54	0.28	0.30	0.50	0.60	0.60	0.50
	-52G/A	f (G)	0.61	0.47	0.72	0.70	0.50	0.40	0.40	0.50
		f (A)	0.39	0.53	0.28	0.30	0.50	0.60	0.60	0.50
	-44C/G	f (C)	0.82	0.92	0.72	0.70	0.94	0.90	0.95	0.79
		f (G)	0.18	0.08	0.28	0.30	0.06	0.10	0.05	0.21
	-20G/A	f (G)	0.58	0.65	0.54	0.60	0.61	0.70	0.65	0.71
		f (A)	0.42	0.35	0.46	0.40	0.39	0.30	0.35	0.29
	79T/A	f (T)	0.81	0.88	0.74	0.70	0.89	0.90	0.95	0.79
		f (A)	0.19	0.12	0.26	0.30	0.11	0.10	0.05	0.21
Exon-2	1654G>A	f (G)	0.97	0.92	1.00	1.00	0.89	0.90	1.00	0.93
		f (A)	0.03	0.08	0	0	0.11	0.10	0	0.07
	1754G/A	f (G)	0.89	0.95	0.85	0.80	0.94	0.95	0.70	0.93
		f (A)	0.11	0.05	0.15	0.20	0.06	0.05	0.30	0.07
	1836A/G	f (A)	0.95	0.85	0.97	0.95	0.72	0.80	0.95	0.93
		f (G)	0.05	0.15	0.03	0.05	0.28	0.20	0.05	0.07
	1873T/C	f (T)	0.97	0.96	1.00	1.00	1.00	0.90	1.00	1.00
		f (C)	0.03	0.04	0	0	0	0.10	0	0

^†NE = Northern European, AfS S = African sub- Sahara, Af-Am = African-American, CHN = Chinese, MEX = Mexican.

CFAR patients of white and black races were self-identified.

MACS patients were white, non-Hispanic.