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. 2013 Jun;141(6):737–746. doi: 10.1085/jgp.201310988

Table 1.

Approximate guide for experimental design

θ n
2 3 4 5 6 7 8
0.85 5 7 8 10 12 15 18
0.8 7 9 12 16 20 26 32
0.75 9 13 17 24 33 44 60
0.7 11 17 26 37 54 78 112
0.65 15 24 38 59 92 143 221
0.6 19 34 57 97 163 272 455
0.55 26 48 90 165 301 548 998
0.5 35 72 146 293 588 1,177 2,356
0.45 49 110 248 553 1,231 2,737 6,048

This table enumerates how many observations (N) would be required to achieve a confidence in excess of 0.99 for various values of θ and n.