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. 2013 Jun;141(6):691–703. doi: 10.1085/jgp.201210937

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© 2013 Ponissery Saidu et al.

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Figure 3. — Patch-clamp analysis of ANO2 isoforms containing or lacking exon 4–encoded sequence. (A) Ca²⁺ and cAMP-gated currents from HEK293T patches expressing the individual isoforms of ANO2 along with the CNGA2 channel. Patches were exposed immediately (15 s) after excision, and the holding potential was −40 mV. (B) Quantification of the peak ANO2 and CNGA2 currents for each expression condition derived from experiments as shown in A. Current (pA) values are means from 9–11 patches ± SEM. *, P < 0.01; **, P < 0.001; Student’s t test.