Figure 5.

Suppression of the trpA1 phenotype by expression of the wild-type trpA1 transgene in pacemaker neurons. Average actograms using flies that were entrained to 12 h light/dark cycles for 3 d at 25°C followed by 6 d of 12 h thermophase (25°C) and 12 h cryophase (16°C) cycles in constant darkness. The warm and cool cycles, which simulate day and night, were the reverse phase from the night and day during the LD cycles (antiphase paradigm). After the temperature entrainment, the flies were kept at 25°C (free run). The white and black bars at the top indicate the LD cycles and the red and blue bars at the bottom indicate the TC cycles. The thermophases and cryophases are highlighted on the actograms with red and blue boxes, respectively. Asterisks indicate sustained peaks that were not detected in the w¹¹¹⁸ actogram. A, w¹¹¹⁸. B, trpA1¹. C, UAS-trpA1-A;trpA1¹. D, UAS-trpA1-A /tim-GAL4;trpA1¹. E, trpA1^GAL4. F, UAS-trpA1-A;trpA1^GAL4.