Figure 10.

Schematic flow chart depicts, complex mRNA life cycle. In generally the expression of biologically active proteins in eukaryotic cells is governed by multiple events: chromatin structure, transcriptional initiation, processing and modification of mRNA transcripts (mRNA is synthesized as precursor heteronuclear RNA: hnRNA and change into mature mRNA molecules), transport of mRNA into cytoplasm (hnRNA processing occurs largely in the nucleus and is accompanied by the binding of mRNA with numerous RNA binding proteins that form messenger ribonucleoprotiens; mRNP), stability or decay of mRNA transcripts, initiation and elongation of mRNA translation, co/post-translation modification and intercellular transport and degradation of the expression protein. The model was adapted and modified from Adeli (2011).