Table 4.
Particle Size Analysis
| OXY40 | TAP50 | TAP250 | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||||||||
| n | M | SD | Med | n | M | SD | Med | n | M | SD | Med | |||||
|
|
||||||||||||||||
| % Tablet weight (wgt) recovered | 24 | 68.9 | 11.2 | 70.6 | 25 | 96.2 | 9.2 | 99.5 | 25 | 93.3 | 14.7 | 98.8 | ||||
| % Recovered tab wgt > 850 μm | 24 | 20.8 | 21.1 | 15.6 | 25 | 97.9 | 7.1 | 100.0 | 25 | 98.7 | 4.6 | 100.0 | ||||
| % Recovered tab wgt < 850 μm | 24 | 79.2 | 21.1 | 84.4 | 25 | 2.1 | 7.1 | 0.0 | 25 | 1.3 | 4.6 | 0.00 | ||||
| # Particles measured by HSIA | 23 | 41,595 | 24,269 | 38,080 | 8 | 1,337 | 1,917 | 440 | 9 | 1,818 | 2,252 | 969 | ||||
| Pairwise Comparisons | TAP50 vs. OXY40 | TAP250 vs. OXY40 | TAP50 vs. TAP250 | |||
|---|---|---|---|---|---|---|
|
| ||||||
| LS Mean Difference | 95% CI | LS Mean Difference | 95% CI | LS Mean Difference | 95% CI | |
| % Tablet wgt recovered | 27.1** | (21.4 to 32.9) | 24.2** | (18.4 to 29.9) | −2.9 | (−8.6 to 2.7) |
| % Recovered tab wgt > 850 μm | 77.0** | (69.8 to 84.2) | 77.8** | (70.6 to 85.0) | 0.8 | (−6.3 to 7.9) |
| % Recovered tab wgt < 850 μm | −77.0** | (−84.2 to 69.8) | −77.8** | (−85.0 to −70.6) | −0.8 | (−7.9 to 6.3) |
| # Particles measured by HSIA | −31,878** | (− 44,041 to −19,725) | −32,878** | (−44,483 to −21,274) | −1000.4 | (−13,679 to 11,678) |
M=Mean, SD=Standard Deviation, Med=Median
**
p<.001