Table 3.
Explant histology scores tabulated.
| Day | Firm |
Pliable |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| None | Minimal | Moderate | Significant | None | Minimal | Moderate | Significant | ||
| Inflammatory cell infiltration | 5 | 9 | 6 | 3 | 0 | 17 | 1 | 0 | 0 |
| 10 | 0 | 18 | 0 | 0 | 5 | 12 | 0 | 1 | |
| 15 | 1 | 15 | 1 | 0 | 0 | 16 | 2 | 0 | |
| 20 | 2 | 12 | 3 | 0 | 5 | 12 | 0 | 0 | |
| 25 | 1 | 17 | 0 | 1 | 3 | 14 | 0 | 0 | |
| 30 | 0 | 16 | 2 | 0 | 2 | 16 | 0 | 0 | |
| Revascularization | 5 | 17 | 1 | 0 | 0 | 18 | 0 | 0 | 0 |
| 10 | 10 | 8 | 0 | 0 | 12 | 6 | 0 | 0 | |
| 15 | 3 | 10 | 4 | 0 | 6 | 11 | 1 | 0 | |
| 20 | 1 | 9 | 6 | 1 | 2 | 10 | 5 | 0 | |
| 25 | 1 | 7 | 8 | 2 | 1 | 9 | 6 | 1 | |
| 30 | 1 | 6 | 6 | 5 | 2 | 7 | 8 | 1 | |
| Recellularization | 5 | 13 | 0 | 0 | 0 | 5 | 13 | 0 | 0 |
| 10 | 0 | 18 | 0 | 0 | 0 | 16 | 2 | 0 | |
| 15 | 0 | 11 | 6 | 0 | 0 | 14 | 4 | 0 | |
| 20 | 0 | 7 | 8 | 2 | 0 | 8 | 8 | 1 | |
| 25 | 0 | 4 | 11 | 3 | 0 | 3 | 12 | 2 | |
| 30 | 0 | 4 | 8 | 6 | 0 | 3 | 13 | 2 | |
PADM: porcine-derived acellular dermal matrix.
At least six slides with three sections—cranial, middle, and caudal (see Figure 1)—at each time point were evaluated for PADM firm and PADM pliable. Each cell represents the number of samples categorized within the specific grouping. Fibroblastic cell infiltration and revascularization of scaffolds increased with time while minimum to mild levels of inflammatory cell infiltration was noted in both PADM firm and pliable.