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. 2013 Jun;15(6):591–599. doi: 10.1593/neo.13158

Figure 4.

Figure 4

Antiangiogenic effects of supernatants collected from virus-infected MGG4 GSCs in vitro. (A) Representative tubular structures formed by HUVECs when grown on a matrigel substrate with supernatants from infected MGG4 GSCs. The bar indicates 0.5 mm. (B) The number of tubes counted when HUVECs were grown in the presence of supernatants from MGG4 GSCs infected with G47Δ-mAngio (mAngio; 14.25 ± 1.11 tubes), G47Δ-mIL12 (mIL12; 14.75 ± 1.44 tubes), G47Δ-mAngio + G47Δ-mIL12 (mAngio + mIL12; 3.75± 0.48 tubes), or EGM (-; 41 ± 2.35 tubes). The bars indicate average number of tubes ± SD. Statistically significant differences were observed for mAngio versus mAngio + mIL12, P < .0001; mIL12 versus mAngio + mIL12, P = .0003; EGM(-) versus mAngio + mIL12, P < .0001; EGM(-) versus mAngio, P < .0001; and EGM(-) versus mIL12, P < .0001.