Effects on average annual lung function change of FEV1 and FVC (ml/year) and FEV1% and FVC% (percent/year) in total longitudinal population1.
| FVC a | FVC% a | FEV1a | FEV1% a | |||||
|---|---|---|---|---|---|---|---|---|
| Estimate | 95% CI b | Estimate | 95% CI b | Estimate | 95% CI b | Estimate | 95% CI b | |
| Dust cloud | ||||||||
| Yes | 7 | (-14.3,28.4) | 0.06 | (-0.54, 0.66) | 7.4 | (-9.5,24.3) | 0.32 | (-0.30,0.95) |
| No | Ref | Ref | Ref | Ref | ||||
| Tobacco | ||||||||
| Heavy | -49.4*** | (-74.8, -24.0) | -1.13** | (-1.85, -0.41) | -25.2* | (-45.3,-5.1) | -0.97* | (-1.72, -0.23) |
| Light/none | Ref | Ref | Ref | Ref | ||||
| Spirometry pattern | ||||||||
| Normal | Ref | Ref | Ref | Ref | ||||
| Low FVC | 42.2** | (16.7, 67.7) | 0.85* | (0.13, 1.58) | 22.6* | (2.1,43.0) | 0.81* | (0.53,1.56) |
| Obstructed | -15.8 | (-52.9, 21.3) | -0.55 | (-1.59, 0.49) | 13 | (-17.0, 42.9) | 0.32 | (-0.79,1.43) |
| Obstructed and low FVC | 80.1** | (25.2,135.0) | 2.55** | (1.04,4.07) | 87.2** | (42.1,132.4) | 3.31*** | (1.68,4.94) |
| Exposure category | ||||||||
| Local workers | Ref | Ref | Ref | Ref | ||||
| Clean-up workers | 35.2* | (4.5, 65.9) | 0.45 | (-0.42,1.31) | 31.7* | (7.4,56.0) | 0.65 | (-0.26,1.55) |
| Resident | 45.8* | (16.6,75.0) | 0.81 | (-0.01,1.63) | 21.6 | (-1.6, 44.8) | 0.6 | (-0.27,1.46) |
| Rescue/recovery | 22.5** | (38.1,126,2) | 2.62*** | (1.44,3.80) | 43.4* | (8.7,78.1) | 1.07 | (-0.17,2.31) |
| other | -11.7 | (-79.8,56.5) | -0.71 | (-2.53, 1.10) | 13.2 | (-42.3,68.6) | -0.22 | (-2.19,1.74) |
| Respiratory symptoms | ||||||||
| No | 27.1 | (-1.9,56.1) | 0.71 | (-0.11, 1.53) | 8.5 | (-14.5, 31.4) | 0.39 | (-0.46, 1.25) |
| Yes | Ref | Ref | Ref | Ref | ||||
1
All results were from linear regression models adjusted with age, gender, race, BMI, income, and lower respiratory symptom.
a
After removing outliers, regression models were fit with 820, 841, 828, and 825 subjects for FEV1, FEV1%, FVC, and FVC% respectively.
b*
: P-value<0.05;
**
: P-value<0.005;
***
: P-value<0.0005