Table 4.
Formulations | (R 2) | ||||||||
---|---|---|---|---|---|---|---|---|---|
Zero order | 1st order | Higuchi | Korsmeyer-Peppas | ||||||
Millipore goat | Membrane cornea | Millipore goat | Membrane cornea | Millipore goat | Membrane cornea | Millipore goat | Membrane cornea |
Mechanism of drug release |
|
VG1 | 0.9286 | 0.8887 | 0.9326 | 0.9176 | 0.9505 | 0.9866 | 0.9126 | 0.9474 | Fickian |
VG2 | 0.9320 | 0.9006 | 0.9227 | 0.9128 | 0.9362 | 0.9414 | 0.8981 | 0.7705 | Non-Fickian |
VG3 | 0.9461 | 0.9207 | 0.9227 | 0.9269 | 0.9452 | 0.9346 | 0.8981 | 0.8073 | Non-Fickian |
VG4 | 0.9298 | 0.8840 | 0.9438 | 0.9077 | 0.9506 | 0.9738 | 0.9337 | 0.8922 | Fickian |
VG5 | 0.9338 | 0.9102 | 0.9402 | 0.9195 | 0.9478 | 0.9388 | 0.9015 | 0.7878 | Fickian |
VG6 | 0.9011 | 0.9250 | 0.8985 | 0.9325 | 0.9183 | 0.9428 | 0.9077 | 0.8304 | Fickian |
VG7 | 0.9376 | 0.8828 | 0.9435 | 0.9059 | 0.9560 | 0.9755 | 0.896 | 0.8947 | Fickian |
VG8 | 0.9587 | 0.9089 | 0.9535 | 0.9179 | 0.9620 | 0.9366 | 0.9451 | 0.7789 | Non-Fickian |
VG9 | 0.8812 | 0.9311 | 0.8632 | 0.9440 | 0.9034 | 0.9750 | 0.9023 | 0.890 | Non-Fickian |