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Colocalization of MDA-MB-231 and U937 cells with areas of ECM degradation. Confocal microscopy representative microphotographs of MDA-MB-231 and U937 cocultures. Collagen degradation (upper left panel), optical image of an MDA-MB-231 cell conglomerate (upper right panel), U937 cells labeled with CellTracker Orange (lower left panel), and the merge of all images (lower right panel). The epithelial morphology of MDA-MB-231 cells is pointed with a white arrow. Optical magnification 200x.
