Table 1.
Overall Characteristics of Post Chemotherapy RPLND Patients
| Non-Nerve- Sparing |
Nerve-Sparing Study Cohort |
p-Value | ||||
|---|---|---|---|---|---|---|
| # | % | # | % | |||
| n | 205 | 135 | ||||
| Age, yrs | Median (IQR) | 34 | (27, 41) | 30 | (24,35) | <0.001 |
| Laterality | Left | 87 | (42%) | 81 | (60%) | 0.001 |
| Right | 112 | (55%) | 54 | (40%) | ||
| Bilateral | 1 | (0%) | 0 | (0%) | ||
| Extragonadal Disease | 5 | (3%) | 0 | (0%) | ||
| Clinical Stage | l | 14 | (7%) | 10 | (7%) | <0.001 |
| lS | 3 | (1%) | 3 | (2%) | ||
| lla | 14 | (7%) | 31 | (23%) | ||
| llb | 48 | (23%) | 40 | (30%) | ||
| llc | 47 | (23%) | 20 | (15%) | ||
| lll | 79 | (39%) | 31 | (23%) | ||
| IGCCCG Risk | Good | 131 | (64%) | 113 | (84%) | 0.001 |
| Intermediate | 35 | (17%) | 15 | (11%) | ||
| Poor | 38 | (19%) | 7 | (5%) | ||
| Missing | 1 | (0%) | 0 | (0%) | ||
| Chemo Intent | Induction | 193 | (94%) | 126 | (93%) | 0.96 |
| Relapse | 11 | (5%) | 7 | (5%) | ||
| Missing | 1 | (1%) | 2 | (2%) | ||
| Chemo Regimen | BEP | 93 | (45%) | 28 | (21%) | <0.001 |
| EP | 108 | (53%) | 107 | (79%) | ||
| Other | 4 | (2%) | 0 | (0%) | ||
| 2nd Line Chemo | 37 | (18%) | 7 | (5%) | 0.001 | |
| Elevated Marker | 42 | (20%) | 7 | (5%) | <0.001 | |
| PC-RP Nodal Size | <2cm | 88 | (43%) | 104 | (77%) | |
| 2–5cm | 54 | (26%) | 22 | (16%) | ||
| >5cm | 54 | (26%) | 9 | (7%) | ||
| missing | 9 | (4%) | 0 | (0%) | ||
| Template | Bilateral With | 138 | (67%) | 36 | (27%) | 0.001 |
| Contralateral Iliacs | ||||||
| Bilateral Without | 54 | (26%) | 99 | (73%) | ||
| Contralateral Iliacs | ||||||
| Other | 12 | (6%) | 0 | (0%) | ||
| Missing | 1 | (1%) | ||||
| Number of Nodes | Median (IQR) | 25 | (20, 40) | 27 | (19,39) | 0.083 |
| Pathology | Fibrosis/Necrosis | 100 | (49%) | 82 | (61%) | <0.001 |
| Teratoma | 80 | (39%) | 53 | (39%) | ||
| Viable Germ Cell | 25 | (12%) | 0 | (0%) | ||
IQR: interquartile range, IGCCCG: International Germ Cell Cancer Collaborative Group, RP: retroperitoneal, PC-RPLND: post-chemotherapy retroperitoneal lymph node dissection