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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Antiviral Res. 2013 Mar 21;98(2):135–143. doi: 10.1016/j.antiviral.2013.03.009

Figure 2. Temporal analysis of tissue and serum virus titers and ALT levels during wt RVFV infection in C57BL/6 mice.

Figure 2

Animals were challenged i.n. or s.c. with 103.9 or 103.3 PFU of RVFV, respectively. Groups of 3 mice were designated for sacrifice on the specified days of infection for analysis of A) serum, B) liver, C) lung, D) spleen, E) kidney, and F) brain virus titers, and G) serum ALT concentrations. Unique symbols on each day post-infection represent values for the same animal across all parameters. The closed and open symbols represent mice challenged i.n. or s.c., respectively. The gray, solid and hashed lines indicate the limits of detection for the i.n. and s.c. challenged animals, respectively. Serum from one of the animals on day 1 was compromised and not included in the analysis. Due to death prior to time of sacrifice, data for several animals in the day 3 and 4 groups could not be obtained.