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Hsf4 controls the expression of Hsp25 in the lens during development. Histological analyses of hsf4+/+hsp25+/−-LacZ lens at P1 to 8-weeks to show the expression of β-gal in developing and mature lens. Note the positive X-gal staining at P2 hsf4+/+hsp25+/−-lacZ while no X-gal staining can be detected in hsf4−/−hsp25+/−-lacZ.
