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. Author manuscript; available in PMC: 2013 May 28.
Published in final edited form as: Bioorg Med Chem Lett. 2008 May 7;18(12):3536–3540. doi: 10.1016/j.bmcl.2008.05.020

Figure 2.

Figure 2

Compounds 10 and 16 were evaluated in a biofilm assay where they showed a dose-dependent pattern with an estimated IC50 around 30–40 μM for compound 10 and 65–75 μM for 16. The corresponding carboxylic acid substituted pilicide 2 displayed a 45 % inhibition at 400 μM. The figure shows the average inhibition of duplicate runs and the standard deviations are shown in error bars.