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. 2008 Jun;84(6):176–188. doi: 10.2183/pjab/84.176

Table 2.

Summary of malignant tumor data for monkeys treated with antineoplastic and immunosupressive agents

Agent No. of monkeysa) Route Daily dose (mg/kg) No. of dead with malignant tumor Carcinogenicity
Doxorubicin hydrochloride 10 iv 0.2 0 no
Doxorubicin hydrochloride 10 iv 0.4 1 no
Doxorubicin hydrochloride 10 iv 1.0 1 no
Cyclophosphamide 23 po 6.0 1 not conclusive
Melphalan 20 ng 0.1 2 not conclusive
Procarbazine 49 sc/po, ip/po, or ip 10 17 yes
MNU 43b) or 44c) po 10 18 yes
a)

Number of animals surviving longer than 6 months after the first dose

b)

See reference 13

c)

See refernce 5