Table 3.
Summary of malignant tumor data for monkeys treated with saccharin, cyclamate, DDT and heterocyclic amines
| Agent | No. of monkeysa) | Route | Daily dose (mg/kg) | No. dead with malignant tumor | Carcinogenicity |
|---|---|---|---|---|---|
| Saccharin | 20 | po | 25 | 0 | no |
| Cyclamate | 10 | po | 100 | 1 | no |
| Cyclamate | 11 | po | 500 | 2 | no |
| DDT | 25 | po | 20 | 2 | not conclusive |
| 1Q | 20 | ng | 10 | 9 | yes |
| 1Q | 20 | ng | 20 | 17 | yes |
| MeIQx | 10 | ng | 20 | 0 | no |
| MeIQx | 10 | ng | 10 | 0 | no |
| PhIP | 10 | ng | 20 | 0 | no |
| PhIP | 10 | ng | 10 | 0 | no |
a)
Number of animals surviving longer than 6 months after the first dose