Table 1.
Demographic data
| Patients | Nonimmunized | MICA-Immunized |
|---|---|---|
| Patients (n) | 51 | 30 |
| Donors | ||
| Age (yr) | 53±13 | 52±16 |
| Men/women, n/n (% men) | 29/22 (56.8) | 10/20 (33.3) |
| Recipients | ||
| Age (yr) | 52±11 | 48±16 |
| Men/women, n/n (% men) | 34/17 (66.6) | 17/13 (56.6) |
| Kidney graft/pancreas and kidney grafts, n/n (% kidney) | 47/4 (92.1) | 20/10 (66.6) |
| Postgraft follow-up time (mo) | 43.1±23.8 | 49.8±30.3 |
| Total HLA-A-B-DR mismatches (n) | 3.6±1.2 | 4.0±1.0 |
| Immunization anti-MICA (%) | None | 30 (100) |
| Time to post-transplant MICA antibody appearance (mo) | NA | 16.4±23.1 |
| Immunization anti-class I (%) | None | 5 (16.6) |
| Immunization anti-class II (%) | None | 4 (13.3) |
| Original disease (n) | ||
| Polycystic kidney disease | 16 | 4 |
| Diabetes mellitus | 7 | 12 |
| Hypertensive nephritis | 6 | 0 |
| Chronic renal insufficiency | 6 | 2 |
| Chronic interstitial nephritis | 4 | 2 |
| IgA nephritis | 2 | 2 |
| Glomerular disease | 2 | 2 |
| Other | 8 | 6 |
Values expressed with a plus/minus sign are the mean ± SD. NA, not applicable.