Figure 2. High dose of Pb ANKA (10⁷ PbA-pRBCs per mouse) could not induce ECM in 3-cure mice.

Three-cure mice were challenged with high dose of PbA (10⁷ PbA-pRBCs per mouse) as compared to 0-cure mice inoculated with normal dose (10⁴ PbA-pRBCs per mouse). After infection, all mice were daily monitored for survival and parasitemia. (A) Survival curves. Statistical analysis was performed by log-rank test, p<0.0002. (B) Kinetics of individual parasitemia of 3-cure and 0-cure mice. Comparisons between two groups of mice on each day was statistically analyzed by Mann-Whitney U test, where NS, p>0.05. n = 6 mice in each group.