Table 7.
MYH3 and DHODH rankings using different null models.
| Gene | FisherRank | FisherP | FisherBHFDR | StoufferRank | StoufferP | StoufferBHFDR |
|---|---|---|---|---|---|---|
| Swissprot null model | ||||||
| DHODH | 4 | 3.8e-05 | 0.05 | 2 | 0.001 | 1.00 |
| MYH3 | 5 | 1.7e-05 | 0.05 | 4 | 0.021 | 1.00 |
| 1000 genomes null model | ||||||
| DHODH | 5 | 4.4e-08 | 0.05 | 2 | 1.9e-06 | 0.05 |
| MYH3 | 3 | 3.8e-14 | 0.05 | 2 | 9.3e-07 | 0.05 |
| Complete genomics null model | ||||||
| DHODH | 5 | 4.6e-08 | 0.05 | 2 | 1.9e-06 | 0.05 |
| MYH3 | 15 | 2.0e-06 | 0.05 | 5 | 2.4e-03 | 1.00 |
Ranks of MYH3 and DHODH differ slightly when different null models are used to estimate p-values for VEST mutation scores.