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Growth-inhibiting effects of 5-Aza-CdR on MCF-7 cells.
Notes: MCF-7 cells were treated with different concentrations of 5-Aza-CdR for 0–72 hours. Cell viability was determined by MTT assay, performed in triplicate. Dose- and time-dependent inhibition of cell growth could be observed after 72 hours (P < 0.05, one-way ANOVA).
Abbreviations: 5-Aza-CdR, 5-aza-2′-deoxycytidine; ANOVA, analysis of variance; MTT, 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; h, hours.
