Table 5.
Enrichment data and genomic location of the RORA-binding enriched regions closest to the selected genes
| Nearest gene | Entrez gene name | MAT score on T (R vs. G) | Pvalue (region) | FDR (%) | Average intensity fold-change (R vs. G) | Chromosome (strand) | Region start | Length (bps) | Number of probes in region |
|---|---|---|---|---|---|---|---|---|---|
|
ITPR1 |
Inositol 1,4,5-triphosphate receptor, type 1 |
17.19 |
0.005 |
<5 |
1.29 |
chr3 (+) |
4,724,792 |
2,804 |
71 |
|
HSD17B10 |
Hydroxysteroid (17-β) dehydrogenase 10 |
14.11 |
0.007 |
<5 |
11.86 |
chrX (−) |
53,483,92 |
1,723 |
42 |
|
A2BP1 (RBFOX1) |
RNA binding protein, fox-1 homolog |
12.86 |
0.009 |
<5 |
1.29 |
chr16 (+) |
7,315,418 |
2,636 |
68 |
|
NLGN1 |
Neuroligin 1 |
7.30 |
0.036 |
<5 |
3.27 |
chr3 (+) |
174,777,672 |
639 |
18 |
|
CYP19A1 (aromatase) |
Cytochrome P450, family 19, subfamily A, polypeptide 1 |
7.02 |
0.040 |
<5 |
1.61 |
chr15 (−) |
49,415,636 |
2,111 |
54 |
| NTRK2 | Neurotrophic tyrosine kinase, receptor, type 2 | 6.72 | 0.044 | <7 | 2.17 | chr9 (+) | 86,412,498 | 966 | 21 |
FDR false discovery rate, G intensity of probes hybridized with DNA fragments immunoprecipitated with nonspecific IgG, MAT model-based analysis of tiling arrays, R intensity of probes hybridized with DNA fragments immunoprecipitated with anti-RORA antibody, T t-statistic.