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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Nucl Med Biol. 2013 Apr 24;40(5):606–617. doi: 10.1016/j.nucmedbio.2013.01.011

Table 2.

Biodistribution studies of 177Lu-MAC0, 177Lu-MAC1 and 177Lu-MAC2 at 24 and 72 h post-injection in HPAC tumor-bearing SCID mice. Data is represented as %ID/g.

24 hours 72 hours
Tissues Lu-MAC0b Lu-MAC1a Lu-MAC2c Lu-MAC0 b Lu-MAC1b Lu-MAC2c
Blood 28.50 ± 6.59 14.85 ± 1.23 17.76 ± 1.57 13.40 ± 1.71 8.54 ± 1.76 8.89 ± 0.65
Bladder 9.09 ± 3.49 1.63 ± 0.94 3.11 ± 0.82 7.15 ± 2.61 2.18 ± 0.25 3.61 ± 0.34
Small Int. 1.36 ± 0.42 0.85 ± 0.15 0.97 ± 0.12 1.25 ± 0.21 0.51 ± 0.09 0.67 ± 0.06
Large Int. 1.48 ± 0.38 0.84 ± 0.09 1.31 ± 0.17 1.25 ± 0.21 0.54 ± 0.09 1.06 ± 0.15
Stomach 1.02 ± 0.21 0.63 ± 0.07 0.80 ± 0.10 0.91 ± 0.14 0.37 ± 0.07 0.52 ± 0.04
Pancreas 2.16 ± 0.66 0.93 ± 0.22 1.35 ± 0.25 2.95 ± 0.55 1.10 ± 0.20 1.10 ± 0.13
Spleen 7.83 ± 3.32 5.09 ± 1.24 4.95 ± 0.49 21.46 ± 4.41 5.63 ± 1.22 5.67 ± 0.75
Kidney 5.22 ± 1.57 2.50 ± 0.59 3.34 ± 0.44 4.20 ± 0.58 1.93 ± 0.38 2.51 ± 0.17
Tumor 4.09 ± 1.41 1.18 ± 0.25 1.64 ± 0.18 6.58 ± 0.93 2.33 ± 0.30 3.49 ± 0.28
Liver 7.27 ± 2.64 3.44 ± 0.82 5.29 ± 0.98 11.36 ± 1.65 3.61 ± 0.63 5.46 ± 0.44
Lung 8.18 ± 2.60 3.81 ± 0.76 4.16 ± 0.37 5.56 ± 1.01 2.66 ± 0.46 3.56 ± 0.16
Heart 6.13 ± 1.75 2.37 ± 0.50 2.72 ± 0.30 5.00 ± 0.75 1.85 ± 0.38 2.26 ± 0.22
Brain 0.91 ± 0.23 0.30 ± 0.10 0.36 ± 0.04 0.57 ± 0.00 0.24 ± 0.05 0.27 ± 0.02
Bone 1.71 ± 0.51 0.85 ± 0.09 1.20 ± 0.16 3.06 ± 0.46 0.68 ± 0.12 1.02 ± 0.11
Muscle 1.36 ± 0.42 0.71 ± 0.13 0.75 ± 0.08 2.38 ± 0.55 1.37 ± 0.39 1.46 ± 0.15

The data is given in mean ± SEM.

a

N = 4,

b

N = 5,

c

N = 6.